Nutraceutical manufacturers rely on cryogens for preservation, processing, and quality control primarily liquid nitrogen, for the preservation, processing, and quality control. These cryogenic techniques are essential for maintaining product quality, efficacy, and shelf life, making them vital to the production of high-quality nutraceuticals. Better-insulated hoses, like vacuum-jacketed hoses, play a key role in these processes by efficiently maintaining the extremely low temperatures required. Enhanced insulation offers specific benefits for each application, ensuring optimal performance and preserving the integrity of the ingredients.
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Applications
Controlled Atmosphere Packaging (CAP)
Cryogens, especially liquid nitrogen, are used in packaging to create an inert atmosphere that displaces oxygen, reducing oxidation and preserving product freshness. To ensure reliable transfer and efficient use, insulated hoses minimize nitrogen loss from evaporation, ensuring more nitrogen reaches the packaging area to maintain a low-oxygen, controlled environment.
Cryogenic Milling and Grinding
Cryogenic milling allows for the precise grinding of heat-sensitive nutraceutical ingredients into fine, consistent powders for capsules, tablets, or powders while protecting delicate bioactive compounds. High-quality, insulated hoses are essential for maintaining the low temperatures needed, minimizing cryogen loss and preventing temperature changes that could affect product quality or cause blockages, ensuring efficient and consistent milling.
Encapsulation and Coating
Cryogens are used to encapsulate or coat nutraceuticals with protective layers to mask flavors, control release rates, and improve stability. Insulated hoses ensure consistent cryogen delivery, stabilizing temperatures during the process and leading to more effective, uniform coating or encapsulation that enhances product stability and quality.
Freeze-Drying (Lyophilization)
Cryogenic freeze-drying is used to preserve nutrients, flavor, and texture in nutraceutical products. When properly conducted, cryogenic freeze-drying results in stable products that can be easily rehydrated. Maintaining a consistently cold environment is essential for moisture removal without compromising the quality of the ingredients. High-quality, well-insulated cryogenic hoses are key to ensuring reliable thermal performance, protecting the integrity of the product throughout the freeze-drying process.
Preserving Sensitive Ingredients
Exposure to heat and oxygen can degrade valuable bioactive compounds including vitamins, probiotics, and enzymes. Without proper insulation, temperature fluctuations can compromise ingredient quality and stability. Nutraceutical manufacturers use cryogenic nitrogen to extend the shelf life of sensitive compounds including vitamins, probiotics, and enzymes. Better insulation helps ensure proper temperature control to maintain compound potency and stability.
PTFE and PFA Tubing
Cryogens are also used in applications that require hoses with smooth internal bores, or requirements for non-metallic wetted surfaces. In these applications, maintain ultra-high purity fluids or prevent unwanted chemical reactions with Insulon Vacuum Jacketed Hose over PTFE or PFA tubing. Insulon Hose + PTFE/PFA assemblies feature a smooth internal bore and non-metallic wetted surfaces.
Additional Resources
The right insulated hoses reduce load on temperature control equipment
Reduce cryogenic boil-off losses up to 45% with Insulon Hose with MLI
